Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 6/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | BECN1 | Q14457 | 3/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14517842 | 0.94 | PRMT5 (0.33) | IDO1NAMPTELANE | |
| SCHEMBL14517815 | 0.92 | CASP1 (0.36) | NAMPTFAAHELANE | |
| SCHEMBL5420765 | 0.91 | BCL2 (0.35) | IDO1BCL2FAAHELANE | |
| SCHEMBL14517849 | 0.90 | ELANE (0.32) | NAMPTFAAHELANE | |
| SCHEMBL14517824 | 0.90 | ELANE (0.34) | FAAHELANE | |
| SCHEMBL13946840 | 0.90 | ELANE (0.34) | FAAHELANE | |
| SCHEMBL5442544 | 0.89 | IDO1 (0.42) | IDO1BCL2NAMPTBECN1 | |
| SCHEMBL14517846 | 0.89 | ELANE (0.32) | FAAHELANE | |
| SCHEMBL13946832 | 0.88 | ELANE (0.34) | FAAHELANE | |
| SCHEMBL14517810 | 0.88 | CASP1 (0.35) | NAMPTFAAHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205291-B2 | High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |