Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13946840 | 0.94 | ELANE (0.34) | ELANEFAAH | |
| SCHEMBL14517846 | 0.93 | ELANE (0.32) | ELANEFAAH | |
| SCHEMBL13946832 | 0.93 | ELANE (0.34) | ELANEFAAH | |
| SCHEMBL14517827 | 0.92 | ELANE (0.32) | ELANEFAAH | |
| SCHEMBL5427057 | 0.92 | ELANE (0.33) | ELANEFAAH | |
| SCHEMBL14517816 | 0.91 | ELANE (0.36) | ELANEFAAH | |
| SCHEMBL4510767 | 0.91 | FAAH (0.33) | ELANEFAAH | |
| SCHEMBL14517825 | 0.90 | ELANE (0.33) | ELANEFAAH | |
| SCHEMBL7636396 | 0.90 | CASP1 (0.33) | ELANEFAAH | |
| SCHEMBL14517826 | 0.90 | ELANE (0.31) | ELANEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205291-B2 | High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |