Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CTH | P32929 | 1/20 | 0.45 |
| ▸ | CBS | P35520 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.33 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 3/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10013986 | 0.97 | TSHR (0.47) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL1827088 | 0.87 | TSHR (0.36) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL26620817 | 0.87 | TSHR (0.36) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL803233 | 0.83 | TSHR (0.33) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL26928 | 0.82 | — | — | |
| SCHEMBL6667392 | 0.81 | EPHX2 (0.38) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL16652816 | 0.81 | TSHR (0.43) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL16821232 | 0.79 | — | — | |
| SCHEMBL2164482 | 0.79 | — | — | |
| SCHEMBL11884627 | 0.79 | TSHR (0.50) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205373-B2 | Enzyme catalyzed organosilicon esters and amides | DOW CORNING CORPORATION (US) | 2007-04-17 | — | — | US | disclosed |
| US-20070021578-A1 | Enzyme catalyzed organosilicon esters and amides | BRANDSTADT KURT F | 2007-01-25 | — | — | US | disclosed |