Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | CBS | P35520 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083533 | 0.87 | ALDH1A1 (0.39) | EPHX2CYP2C19TSHRCES2THRB | |
| SCHEMBL2781555 | 0.84 | THRB (0.41) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL10001230 | 0.84 | CES2 (0.46) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL10013986 | 0.84 | TSHR (0.47) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL20535086 | 0.82 | CES2 (0.46) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL20534923 | 0.82 | EPHX2 (0.42) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL23405410 | 0.81 | CES2 (0.44) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL22922080 | 0.81 | CES2 (0.44) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL7713583 | 0.81 | CES2 (0.50) | EPHX2CYP2C19TSHRCTHCBS | |
| SCHEMBL18660231 | 0.81 | CES2 (0.50) | EPHX2CYP2C19TSHRCTHCBS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910331-B1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-09-08 | — | — | EP | disclosed |