Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1618491 | 0.95 | — | — | |
| SCHEMBL11956760 | 0.84 | TSHR (0.32) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL12210430 | 0.83 | HSD17B10 (0.33) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL14518488 | 0.83 | TSHR (0.45) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL10013986 | 0.80 | TSHR (0.47) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL430310 | 0.75 | — | — | |
| SCHEMBL7635904 | 0.73 | — | — | |
| SCHEMBL16134336 | 0.73 | BLM (0.50) | TSHR | |
| SCHEMBL15686503 | 0.73 | TSHR (0.36) | TSHR | |
| SCHEMBL27356622 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404222-B2 | Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution | NEKTAR THERAPEUTICS (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120071627-A1 | Soluble, Degradable Poly(ethylene glycol) Derivatives for Controllable Release of Bound Molecules into Solution | NEKTAR THERAPEUTICS (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071627-A1 | Soluble, Degradable Poly(ethylene glycol) Derivatives for Controllable Release of Bound Molecules into Solution | IDE, EGFR, IDUA | TSHR 2551/4885CTH 1487/4885CBS 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.