Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365273 | 1.00 | ADORA3 (0.66) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL14518674 | 0.91 | ADORA3 (0.56) | ADORA3ADORA1ADORA2A | |
| SCHEMBL14518672 | 0.89 | ADORA3 (0.66) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL5359756 | 0.84 | ADORA3 (0.52) | ADORA3ADORA1ADORA2A | |
| SCHEMBL5359757 | 0.84 | ADORA3 (0.52) | ADORA3ADORA1ADORA2A | |
| SCHEMBL14518680 | 0.83 | ADORA3 (0.73) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL5364017 | 0.83 | ADORA3 (0.73) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL6426666 | 0.80 | ADORA3 (1.00) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL935019 | 0.80 | ADORA3 (1.00) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL14518669 | 0.79 | ADORA3 (0.55) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199127-B2 | Purine nucleosides | UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-04-03 | — | — | US | disclosed |