Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.66 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 5/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518669 | 0.90 | ADORA3 (0.55) | ADORA3ADORA1ADORA2AHSP90B1CHKA | |
| SCHEMBL5363882 | 0.90 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AHSP90B1CHKA | |
| SCHEMBL14518677 | 0.89 | ADORA3 (0.66) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL5365273 | 0.89 | ADORA3 (0.66) | ADORA3ADORA1ADORA2APPARGPPARD | |
| SCHEMBL14543434 | 0.88 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AHSP90B1CHKA | |
| SCHEMBL5363887 | 0.84 | ADORA3 (0.48) | ADORA3ADORA1ADORA2AHSP90B1CHKA | |
| SCHEMBL5372681 | 0.81 | ADORA3 (0.48) | ADORA3ADORA1ADORA2AHSP90B1 | |
| SCHEMBL5369682 | 0.81 | ADORA3 (0.48) | ADORA3ADORA1ADORA2AHSP90B1 | |
| SCHEMBL14518674 | 0.80 | ADORA3 (0.56) | ADORA3ADORA1ADORA2A | |
| SCHEMBL5365876 | 0.80 | ADORA3 (1.00) | ADORA3ADORA1ADORA2APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199127-B2 | Purine nucleosides | UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-04-03 | — | — | US | disclosed |