Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 8/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14572440 | 0.79 | HTR6 (0.56) | LOXLOXL2MAOAHTR6MAPT | |
| SCHEMBL14519928 | 0.78 | CA2 (0.49) | HTR6VDR | |
| SCHEMBL4250025 | 0.76 | HTR6 (0.56) | LOXLOXL2MAOAHTR6HSD17B2 | |
| SCHEMBL9235944 | 0.76 | LOX (0.61) | LOXLOXL2MAOAHTR6 | |
| SCHEMBL787866 | 0.76 | HTR6 (0.56) | LOXLOXL2MAOAHTR6ALDH1A1 | |
| SCHEMBL9971313 | 0.76 | HTR6 (0.56) | LOXLOXL2MAOAHTR6MAPT | |
| SCHEMBL14502555 | 0.76 | HTR6 (0.56) | LOXLOXL2MAOAHTR6 | |
| SCHEMBL12793721 | 0.75 | LOX (0.51) | LOXLOXL2MAOAHTR6 | |
| SCHEMBL11125174 | 0.75 | LOX (0.53) | LOXLOXL2MAOAHTR6MAPT | |
| Hydrochloric Acid SCHEMBL27583302 | 0.74 | LOX (0.54) | LOXLOXL2MAOAHTR6HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | LOX 2729/4885LOXL2 3263/4885MAOA 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.