SCHEMBL14520261

SCHEMBL14520261

CC(C)(C=O)CNC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107183 0.74
SCHEMBL9936326 0.72
SCHEMBL13535959 0.70
SCHEMBL2250950 0.69
SCHEMBL18768100 0.69 ADH1B (0.32)
SCHEMBL2426544 0.69 L3MBTL1 (0.31) NPSR1
SCHEMBL4203690 0.67 CYP2D6 (0.36)
SCHEMBL20280407 0.67 ADH1B (0.42)
SCHEMBL14450654 0.67 NPSR1 (0.38) NPSR1
SCHEMBL4346571 0.65 NPSR1 (0.34) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007067537-A1 PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS OSI PHARMACEUTICALS, INC. (US) 2007-06-14 WO disclosed