Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | HTR1D | P28221 | 2/20 | 0.67 |
| ▸ | DRD3 | P35462 | 2/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520859 | 0.88 | HTR7 (0.51) | HTR7DRD2HTR1DDRD3TMEM97 | |
| SCHEMBL14520858 | 0.87 | HTR7 (0.50) | HTR7DRD2HTR1DDRD3TMEM97 | |
| SCHEMBL14520860 | 0.86 | HTR7 (0.48) | HTR7DRD2HTR1DDRD3TMEM97 | |
| SCHEMBL14520857 | 0.82 | HTR7 (0.67) | HTR7DRD2HTR1DDRD3SIGMAR1 | |
| Sb-258719 SCHEMBL2471088 | 0.80 | HTR7 (1.00) | HTR7DRD2HTR1DDRD3HTR1A | |
| Sb-258719 SCHEMBL2471089 | 0.80 | HTR7 (1.00) | HTR7DRD2HTR1DDRD3HTR1A | |
| Sb-258719 SCHEMBL29774472 | 0.80 | HTR7 (1.00) | HTR7DRD2HTR1DDRD3HTR1A | |
| Sb-258719 SCHEMBL3688509 | 0.80 | HTR7 (0.98) | HTR7DRD2HTR1DDRD3TMEM97 | |
| SCHEMBL14520861 | 0.79 | HTR7 (0.50) | HTR7DRD2HTR1DDRD3TMEM97 | |
| SCHEMBL14520864 | 0.72 | HTR7 (0.53) | HTR7DRD2HTR1DDRD3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088052-A1 | Sulfonamide derivatives as 5ht7 receptor antagonists | ASTON UNIVERSITY (GB) | 2007-04-19 | — | — | US | disclosed |
| US-20070088052-A1 | Sulfonamide derivatives as 5ht7 receptor antagonists | ASTON UNIVERSITY (GB) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088052-A1 | Sulfonamide derivatives as 5ht7 receptor antagonists | HTR7, HTR2B, HTR2C | HTR7 1/4885DRD2 57/4885HTR1D 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.