Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 18/20 | 0.67 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520860 | 0.83 | HTR7 (0.48) | HTR7DRD3HTR1DDRD2SIGMAR1 | |
| SCHEMBL14520856 | 0.82 | HTR7 (0.67) | HTR7DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL14520859 | 0.81 | HTR7 (0.51) | HTR7DRD3HTR2CHTR1DDRD2 | |
| SCHEMBL14520858 | 0.80 | HTR7 (0.50) | HTR7DRD3HTR2CHTR1DDRD2 | |
| SCHEMBL14520861 | 0.76 | HTR7 (0.50) | HTR7DRD3HTR1DDRD2SIGMAR1 | |
| SCHEMBL14520863 | 0.75 | HTR7 (0.56) | HTR7DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL8552181 | 0.73 | HTR7 (0.77) | HTR7DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL8553908 | 0.71 | HTR7 (1.00) | HTR7DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL14520862 | 0.71 | HTR7 (0.58) | HTR7DRD3HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8593597 | 0.70 | HTR7 (0.98) | HTR7DRD3HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070088052-A1 | Sulfonamide derivatives as 5ht7 receptor antagonists | ASTON UNIVERSITY (GB) | 2007-04-19 | — | — | US | disclosed |
| US-20070088052-A1 | Sulfonamide derivatives as 5ht7 receptor antagonists | ASTON UNIVERSITY (GB) | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088052-A1 | Sulfonamide derivatives as 5ht7 receptor antagonists | HTR7, HTR2B, HTR2C | HTR7 1/4885DRD3 171/4885HTR1A 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.