SCHEMBL1452483

SCHEMBL1452483

CO[SiH](OC)OC(C)CCCNCCN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.38
CA6 P23280 5/20 0.38
CA7 P43166 5/20 0.38
CA9 Q16790 5/20 0.38
CA14 Q9ULX7 5/20 0.38
CA5B Q9Y2D0 5/20 0.38
CA2 P00918 4/20 0.38
CA4 P22748 4/20 0.38
CA5A P35218 4/20 0.38
CA3 P07451 3/20 0.38
MEN1 O00255 2/20 0.36
RECQL P46063 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 3/20 0.34
ALOX15 P16050 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
CA1 P00915 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453189 0.83
SCHEMBL27881184 0.76 CA12 (0.56) CA12CA6CA7CA9CA14
SCHEMBL1312061 0.74 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL238152 0.73 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL27557375 0.73 CA12 (0.39) CA12CA6CA7CA9CA14
SCHEMBL28080475 0.71 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL3154947 0.71 ENPEP (0.30)
SCHEMBL28399614 0.70 CA12 (0.41) CA12CA6CA7CA9CA14
SCHEMBL28428422 0.70 CA12 (0.37) CA12CA6CA7CA9CA14
SCHEMBL6448342 0.70 CA12 (0.37) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2233531-B2 Curable composition KANEKA CORP (JP) 2018-11-28 EP disclosed
EP-1832627-B2 CURABLE COMPOSITION KANEKA CORP (JP) 2018-06-13 EP disclosed
EP-2233532-B1 Curable composition KANEKA CORP (JP) 2016-08-10 EP disclosed
EP-2233531-B1 Curable composition KANEKA CORP (JP) 2014-05-07 EP disclosed
US-20140039133-A1 CURABLE COMPOSITION AND METHODS FOR IMPROVING RECOVERY PROPERTIES AND CREEP PROPERTIES KANEKA CORPORATION (JP) 2014-02-06 US disclosed
US-8586688-B2 Curable composition and method for improving recovery properties and creep properties KANEKA CORPORATION (JP) 2013-11-19 US disclosed
US-20110172372-A1 CURABLE COMPOSITION AND METHOD FOR IMPROVING RECOVERY PROPERTIES AND CREEP PROPERTIES KANEKA CORPORATION (JP) 2011-07-14 US disclosed
US-7910682-B2 Curable composition and methods for improving recovery properties and creep properties KANEKA CORPORATION (JP) 2011-03-22 US disclosed
EP-2233531-A1 Curable composition Kaneka Corporation (JP) 2010-09-29 EP disclosed
EP-2233532-A1 Curable composition Kaneka Corporation (JP) 2010-09-29 EP disclosed
EP-1832627-B1 Curable composition and method for improving recovery properties and creep properties KANEKA CORP (JP) 2010-09-08 EP disclosed
EP-1566412-B1 CURABLE COMPOSITION AND METHOD FOR IMPROVING RECOVERY PROPERTIES AND CREEP PROPERTIES KANEKA CORP (JP) 2007-09-26 EP disclosed
EP-1832627-A2 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2007-09-12 EP disclosed
US-20060128919-A1 Curable composition and methods for improving recovery properties and creep properties KANEKA CORPORATION (JP) 2006-06-15 US disclosed
EP-1566412-A1 CURABLE COMPOSITION AND METHOD FOR IMPROVING RECOVERY PROPERTIES AND CREEP PROPERTIES KANEKA CORPORATION (JP) 2005-08-24 EP disclosed