SCHEMBL1452492

SCHEMBL1452492

Cc1cn(OP(=O)(O)OP(=O)(O)OP(=O)(O)O)c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.44
▸ POLA1 P09884 1/20 0.44
▸ POLD1 P28340 1/20 0.44
▸ TYMP P19971 4/20 0.43
▸ TK1 P04183 3/20 0.37
▸ MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3364511 1.00 POLB (0.44) POLBPOLA1POLD1TYMPTK1
SCHEMBL3436939 0.97 TYMP (0.45) POLBPOLA1POLD1TYMPTK1
SCHEMBL28570790 0.96 TYMP (0.44) POLBPOLA1POLD1TYMPTK1
SCHEMBL446614 0.87 POLA1 (0.35) POLBPOLA1POLD1TYMP
SCHEMBL447317 0.86 POLB (0.38) POLBPOLA1POLD1TYMPTK1
SCHEMBL28563636 0.86 POLB (0.38) POLBPOLA1POLD1TYMPTK1
SCHEMBL4342113 0.85 TYMP (0.49) TYMPTK1MAPK1
SCHEMBL28575356 0.83 TYMP (0.48) TYMPTK1MAPK1
SCHEMBL4816453 0.83 P2RY6 (0.36) POLBPOLA1POLD1
SCHEMBL20541413 0.79 TYMP (0.40) POLBPOLA1POLD1TYMPTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4596713-A1 DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF 4basebio UK Ltd (GB) 2025-08-06 — — EP claimed
CN-115427586-B Recovery phase in large-scale parallel sequencing 深圳华大智造科技股份有限公司 2025-03-28 — — CN claimed
EP-4121554-B1 RESTORING PHASE IN MASSIVELY PARALLEL SEQUENCING MGI TECH CO LTD (CN) 2024-10-30 — — EP claimed
US-20230129228-A1 RESTORING PHASE IN MASSIVELY PARALLEL SEQUENCING MGI TECH CO., LTD. (CN) 2023-04-27 — — US claimed
EP-4121554-A1 RESTORING PHASE IN MASSIVELY PARALLEL SEQUENCING MGI Tech Co., Ltd. (CN) 2023-01-25 — — EP claimed
CN-115427586-A Recovery phase in massively parallel sequencing 深圳华大智造科技股份有限公司 2022-12-02 — — CN claimed
CN-115248240-A DNAzyme-based two-channel electrochemical method and application research thereof in lead ion detection 宁波大学 2022-10-28 — — CN claimed
CN-113156122-A Fluorescent sensor for detecting exosome PD-L1 and preparation and application thereof 重庆医科大学 2021-07-23 — — CN claimed
CN-111118211-A Bovine sarcoidosis detection kit and method based on loop-mediated isothermal amplification technology 山东冈津生物工程有限公司 2020-05-08 — — CN claimed
US-9066866-B2 Direct cellular energy delivery system UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2015-06-30 — — US claimed
US-20100317005-A1 Modified Nucleotides and Methods for Making and Use Same Life Technologies Corporation (US) 2010-12-16 — — US claimed
CN-122029175-A Modified nucleotide for improving chain offset, preparation method and application thereof 深圳华大智造科技股份有限公司 2026-05-12 — — CN disclosed
EP-4596713-A1 DNA WITH ENHANCED RESISTANCE AGAINST EXONUCLEASES AND METHODS FOR THE PRODUCTION THEREOF 4basebio UK Ltd (GB) 2025-08-06 — — EP disclosed
CN-119790161-A Use of heteroaromatic compounds in nucleic acid detection 深圳华大生命科学研究院 2025-04-08 — — CN disclosed
CN-119753111-A Method for sequencing polynucleotides 青岛华大智造科技有限责任公司 2025-04-04 — — CN disclosed
EP-0832281-A1 METHOD FOR DETECTING NUCLEIC ACID SEQUENCES USING COMPETITIVE AMPLIFICATION Abbott Laboratories (US) 1998-04-01 — — EP disclosed
US-5667974-A AMPLIFICATION REACTION OF NUCLEIC ACIDS ON SAMPLES AND DETECTION OF SEQUENCES ON TARGETS ABBOTT LABORATORIES (US) 1997-09-16 — — US disclosed
WO-1996040996-A1 METHOD FOR DETECTING NUCLEIC ACID SEQUENCES USING COMPETITIVE AMPLIFICATION ABBOTT LABORATORIES (US) 1996-12-19 — — WO disclosed
EP-0360677-B1 Method and equipment for the identification of DNA bases COMMISSARIAT ENERGIE ATOMIQUE (FR) 1994-04-06 — — EP disclosed
EP-0360677-A1 Method and equipment for the identification of DNA bases COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1990-03-28 — — EP disclosed
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