Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | POLD1 | P28340 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 4/20 | 0.43 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452492 | 1.00 | POLB (0.44) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL3436939 | 0.97 | TYMP (0.45) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL28570790 | 0.96 | TYMP (0.44) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL446614 | 0.87 | POLA1 (0.35) | POLBPOLA1POLD1TYMP | |
| SCHEMBL447317 | 0.86 | POLB (0.38) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL28563636 | 0.86 | POLB (0.38) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL4342113 | 0.85 | TYMP (0.49) | TYMPTK1MAPK1 | |
| SCHEMBL28575356 | 0.83 | TYMP (0.48) | TYMPTK1MAPK1 | |
| SCHEMBL4816453 | 0.83 | P2RY6 (0.36) | POLBPOLA1POLD1 | |
| SCHEMBL20541413 | 0.79 | TYMP (0.40) | POLBPOLA1POLD1TYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921532-B2 | Phospholink nucleotides for sequencing applications | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140065607-A1 | PHOSPHOLINK NUCLEOTIDES FOR SEQUENCING APPLICATIONS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-03-06 | — | — | US | disclosed |
| US-8580539-B2 | Phospholink nucleotides for sequencing applications | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130122490-A1 | PHOSPHOLINK NUCLEOTIDES FOR SEQUENCING APPLICATIONS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-8367813-B2 | Phospholink nucleotides for sequencing applications | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100167299-A1 | PHOSPHOLINK NUCLEOTIDES FOR SEQUENCING APPLICATIONS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2010057185-A1 | PHOSPHOLINK NUCLEOTIDES FOR SEQUENCING APPLICATIONS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167299-A1 | PHOSPHOLINK NUCLEOTIDES FOR SEQUENCING APPLICATIONS | POLN, DTYMK, POLRMT | POLB 18/4885POLA1 150/4885POLD1 372/4885 |
| US-20140065607-A1 | PHOSPHOLINK NUCLEOTIDES FOR SEQUENCING APPLICATIONS | POLN, DTYMK, POLRMT | POLB 17/4885POLA1 133/4885POLD1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.