SCHEMBL3436939

SCHEMBL3436939

Cc1cn(OP(=O)(O)OP(=O)(O)O)c(=O)[nH]c1=O

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 4/20 0.45
▸ POLB P06746 2/20 0.41
▸ POLA1 P09884 1/20 0.41
▸ POLD1 P28340 1/20 0.41
▸ TK1 P04183 3/20 0.38
▸ MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28570790 0.98 TYMP (0.44) TYMPPOLBPOLA1POLD1TK1
SCHEMBL3364511 0.97 POLB (0.44) TYMPPOLBPOLA1POLD1TK1
SCHEMBL1452492 0.97 POLB (0.44) TYMPPOLBPOLA1POLD1TK1
SCHEMBL4342113 0.87 TYMP (0.49) TYMPTK1MAPK1
SCHEMBL28575356 0.86 TYMP (0.48) TYMPTK1MAPK1
SCHEMBL446614 0.84 POLA1 (0.35) TYMPPOLBPOLA1POLD1
SCHEMBL447317 0.83 POLB (0.38) TYMPPOLBPOLA1POLD1TK1
SCHEMBL28563636 0.83 POLB (0.38) TYMPPOLBPOLA1POLD1TK1
SCHEMBL20541413 0.81 TYMP (0.40) TYMPPOLBPOLA1POLD1TK1
SCHEMBL6911384 0.80 TYMP (0.44) TYMPTK1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9066866-B2 Direct cellular energy delivery system UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2015-06-30 — — US claimed
CN-122029175-A Modified nucleotide for improving chain offset, preparation method and application thereof 深圳华大智造科技股份有限公司 2026-05-12 — — CN disclosed
US-20260124229-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2026-05-07 — — US disclosed
US-20260124228-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2026-05-07 — — US disclosed
US-20260115219-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI LLC (US) 2026-04-30 — — US disclosed
US-12539309-B2 Compositions comprising circular polyribonucleotides and uses thereof FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2026-02-03 — — US disclosed
US-20250381211-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2025-12-18 — — US disclosed
US-12480117-B2 Compositions comprising modified circular polyribonucleotides and uses thereof FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2025-11-25 — — US disclosed
US-12357653-B2 Compositions comprising circular polyribonucleotides and uses thereof FLAGSHIP PIONEERING INNOVATIONS VI, LLC (US) 2025-07-15 — — US disclosed
CN-119790161-A Use of heteroaromatic compounds in nucleic acid detection 深圳华大生命科学研究院 2025-04-08 — — CN disclosed
US-7807881-B2 Methods to confer herbicide resistance ATHENIX CORP. (US) 2010-10-05 — — US disclosed
US-20090241219-A1 GDC-2 GENES CONFERRING HERBICIDE RESISTANCE ATHENIX CORPORATION (US) 2009-09-24 — — US disclosed
US-20090148958-A1 NUCLEOTIDE-TRANSITION METAL COMPLEX CATALYST ONECELL INC. 2009-06-11 — — US disclosed
US-7538262-B2 GDC-2 genes conferring herbicide resistance ATHENIX CORPORATION (US) 2009-05-26 — — US disclosed
US-20070107078-A1 Methods to confer herbicide resistance ATHENIX CORPORATION (US) 2007-05-10 — — US disclosed
US-20060021094-A1 GDC-2 genes conferring herbicide resistance ATHENIX CORPORATION (US) 2006-01-26 — — US disclosed
EP-1601774-A2 GDC-2 GENES CONFERRING HERBICIDE RESISTANCE Athenix Corporation (US) 2005-12-07 — — EP disclosed
US-20050204436-A1 Using vector transformation to generate glyphosate resistant crop plants ATHENIX CORPORATION (US) 2005-09-15 — — US disclosed
WO-2005003362-A2 METHODS TO CONFER HERBICIDE RESISTANCE ATHENIX CORPORATION (US) 2005-01-13 — — WO disclosed
WO-2004111245-A2 GDC-2 GENES CONFERRING HERBICIDE RESISTANCE ATHENIX CORPORATION (US) 2004-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260124229-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF RNGTT, RPL21, RPL17 TYMP 208/4885POLB 225/4885POLA1 357/4885
US-12539309-B2 Compositions comprising circular polyribonucleotides and uses thereof EIF4B, IGF2BP3, EIF4A3 TYMP 3519/4885POLB 1549/4885POLA1 3898/4885
US-20260115219-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF UPF1, CPSF6, RNGTT TYMP 390/4885POLB 395/4885POLA1 633/4885
US-20260124228-A1 COMPOSITIONS COMPRISING CIRCULAR POLYRIBONUCLEOTIDES AND USES THEREOF RNGTT, RPL30, EIF4A2 TYMP 313/4885POLB 343/4885POLA1 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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