SCHEMBL145250

SCHEMBL145250

CN(C)C1CCCCC1N

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20370299 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL2549893 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL5676529 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL30962277 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL1440790 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL1071722 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL187419 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL13993046 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL113492 1.00 THRB (0.47) THRBMEN1KMT2A
SCHEMBL15572000 0.97 THRB (0.45) THRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5312 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4613745-A2 PROCESS FOR PREPARING A COT INHIBITOR COMPOUND Gilead Sciences, Inc. (US) 2025-09-10 EP claimed
EP-4608796-A1 PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-09-03 EP claimed
US-12365666-B2 Process for preparing a Cot inhibitor compound GILEAD SCIENCES, INC. (US) 2025-07-22 US claimed
WO-2025039251-A1 NITROGEN-CONTAINING POLYMER CAPABLE OF ACHIEVING LOW-ENERGY ULTRAVIOLET CLEANING ABLATION, PREPARATION METHOD THEREFOR AND USE THEREOF 深圳先进电子材料国际创新研究院 2025-02-27 WO claimed
US-12122788-B2 Process of making CFTR modulators VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-10-22 US claimed
US-20240262809-A1 METHOD FOR PREPARING INTERMEDIATE FOR SYNTHESIS OF XANTHINE OXIDASE INHIBITOR LG CHEM, LTD. (KR) 2024-08-08 US claimed
WO-2024137495-A9 FOSTEMSAVIR INTERMEDIATES AND PROCESS FOR THE PREPARATION THEREOF NAVINTA, LLC (US) 2024-07-25 WO claimed
US-20240239768-A1 METHOD FOR PREPARING XANTHINE OXIDASE INHIBITOR LG CHEM, LTD. (KR) 2024-07-18 US claimed
CN-118290713-A Preparation method and application of NNO (N-phenylene-imine) lactide ring-opening polymerization catalyst 吉林大学 2024-07-05 CN claimed
CN-115894884-B Trifunctional organic catalyst and preparation method and application thereof 浙江大学 2024-07-05 CN claimed
EP-1910304-A2 THERAPEUTIC AGENTS AstraZeneca AB (SE) 2008-04-16 EP claimed
US-7345194-B1 Process for the synthesis of 2,5-dihydroxyterephthalic acid E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-18 US claimed
US-7335791-B1 Process for the synthesis of hydroxy aromatic acids E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-02-26 US claimed
WO-2007010222-A2 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2007-01-25 WO claimed
US-20060247440-A1 Processes for the preparation of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine ENANTA PHARMACEUTICALS, INC. 2006-11-02 US claimed
EP-1713796-A1 PROCESS FOR PREPARING SUBSTITUTED BENZOPYRAN COMPOUNDS SK CHEMICALS CO., LTD. (KR) 2006-10-25 EP claimed
WO-2005077942-A1 PROCESS FOR PREPARING SUBSTITUTED BENZOPYRAN COMPOUNDS SK CHEMICALS, CO., LTD. (KR) 2005-08-25 WO claimed
EP-0614664-B2 Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-01-08 EP claimed
EP-0614664-B1 Quinolonecarboxylic acid derivatives, their preparation and their use as cell adhesion inhibitors TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-09-16 EP claimed
US-5519024-A CELL ADHESION INHIBITOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-05-21 US claimed