Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263773 | 0.76 | HRH3 (0.73) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL15932391 | 0.75 | RAB9A (0.56) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL30874707 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL19174232 | 0.73 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL13325910 | 0.73 | SMN1; SMN2 (0.93) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL4727102 | 0.73 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL23754485 | 0.72 | NPC1 (0.63) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL1691516 | 0.72 | RAB9A (0.60) | SMN1; SMN2TP53HRH3RAB9ANPC1 | |
| SCHEMBL28437603 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2TP53RAB9ANPC1KDM4E | |
| SCHEMBL1691344 | 0.70 | RAB9A (0.72) | SMN1; SMN2TP53RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268478-B1 | PHENYL-SUBSTITUTED IMIDAZOPYRIDINES | ORTHO MCNEIL PHARM INC (US) | 2007-05-02 | — | — | EP | disclosed |