Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12892067 | 0.86 | PTP4A3 (0.65) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8174040 | 0.80 | PTP4A3 (0.71) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8174037 | 0.80 | PTP4A3 (0.71) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL14226382 | 0.80 | NAT1 (0.69) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL15097026 | 0.74 | NAT1 (0.59) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7557609 | 0.74 | NAT1 (1.00) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7557614 | 0.74 | NAT1 (1.00) | NAT1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL8167434 | 0.73 | PIM1 (0.75) | NAT1HPGDNPC1RAB9AMYC | |
| SCHEMBL8167436 | 0.73 | PIM1 (0.75) | NAT1HPGDNPC1RAB9AMYC | |
| SCHEMBL14463945 | 0.73 | GSK3B (0.47) | NAT1MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429763-B1 | NOVEL LIGANDS FOR THE HisB10 Zn2+ SITES OF THE R-STATE INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-05-30 | — | — | EP | disclosed |