Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269617 | 0.88 | MGLL (0.48) | MGLLKDM4EHPGDALDH1A1BRD4 | |
| SCHEMBL13213055 | 0.84 | MGLL (0.53) | MGLLKDM4EHPGDALDH1A1BRD4 | |
| SCHEMBL14529223 | 0.80 | MGLL (0.43) | MGLLKDM4EHPGDALDH1A1BRD4 | |
| SCHEMBL5268500 | 0.78 | PTGS2 (0.48) | MGLLHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5265663 | 0.77 | CHRNA7 (0.39) | MGLLHPGDMALT1MEN1MAPT | |
| SCHEMBL5269952 | 0.77 | MGLL (0.39) | MGLLHPGDMALT1NPC1RAB9A | |
| SCHEMBL2915944 | 0.75 | MGLL (0.60) | MGLLKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL5268336 | 0.73 | CHRNA7 (0.39) | MGLLHPGDMALT1SMN1; SMN2MEN1 | |
| SCHEMBL5270001 | 0.72 | MGLL (0.44) | MGLLKDM4EHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL2921268 | 0.72 | MGLL (0.51) | MGLLKDM4EHPGDALDH1A1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |