Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 3/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NAE1 | Q13564 | 1/20 | 0.41 |
| ▸ | UBA3 | Q8TBC4 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530301 | 1.00 | OPRD1 (0.54) | OPRD1KCNH2KDM1AHSD11B1HDAC1 | |
| SCHEMBL5313407 | 0.88 | HSD11B1 (0.55) | OPRD1KDM1AHSD11B1HDAC1HDAC8 | |
| SCHEMBL5314419 | 0.88 | HSD11B1 (0.55) | OPRD1KDM1AHSD11B1HDAC1HDAC8 | |
| SCHEMBL1222691 | 0.88 | HSD11B1 (0.55) | OPRD1KDM1AHSD11B1HDAC1HDAC8 | |
| SCHEMBL14272834 | 0.86 | HSD11B1 (0.46) | KDM1AHSD11B1HDAC1HDAC8HDAC6 | |
| SCHEMBL14300919 | 0.86 | HSD11B1 (0.46) | KDM1AHSD11B1HDAC1HDAC8HDAC6 | |
| SCHEMBL6588859 | 0.83 | HDAC1 (0.44) | KDM1AHSD11B1HDAC1HDAC8HDAC6 | |
| SCHEMBL31096660 | 0.83 | KDM1A (0.46) | KDM1AHDAC1HDAC8HDAC6GPR119 | |
| SCHEMBL3752156 | 0.83 | KDM1A (0.46) | KDM1AHDAC1HDAC8HDAC6GPR119 | |
| SCHEMBL6394296 | 0.83 | KDM1A (0.46) | KDM1AHDAC1HDAC8HDAC6GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |