Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736130 | 0.85 | SIGMAR1 (0.37) | SIGMAR1NPY5RHTR2CDRD2 | |
| SCHEMBL16835957 | 0.81 | AVPR1A (0.49) | SIGMAR1NPY5RHTR2AHTR2CHTR2B | |
| SCHEMBL22057312 | 0.80 | SIGMAR1 (0.37) | SIGMAR1HTR7HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL20955226 | 0.79 | SIGMAR1 (0.36) | SIGMAR1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL737225 | 0.78 | HRH3 (0.46) | SIGMAR1NPY5RHTR7HTR2AHTR2C | |
| SCHEMBL1276265 | 0.78 | HTR2C (0.41) | SIGMAR1NPY5RHTR2AHTR2CHTR2B | |
| SCHEMBL4369276 | 0.78 | AVPR1A (0.49) | SIGMAR1NPY5RHTR2CHTR2BDRD2 | |
| Hydrochloric Acid SCHEMBL20955703 | 0.77 | HRH3 (0.45) | SIGMAR1NPY5RHTR7HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL1998577 | 0.77 | AVPR1A (0.48) | SIGMAR1NPY5RHTR2CHTR2BDRD2 | |
| SCHEMBL11832778 | 0.75 | AVPR1A (0.50) | SIGMAR1NPY5RCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057775-A1 | SPIROPIPERIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |