Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530331 | 0.85 | SIGMAR1 (0.49) | SIGMAR1NPY5RDRD2HTR2C | |
| SCHEMBL1276265 | 0.77 | HTR2C (0.41) | SIGMAR1NPY5RDHODHDRD2HTR2C | |
| SCHEMBL16835957 | 0.77 | AVPR1A (0.49) | SIGMAR1NPY5RAVPR1ADHODHDRD2 | |
| SCHEMBL4369276 | 0.75 | AVPR1A (0.49) | SIGMAR1NPY5RAVPR1ADHODHDRD2 | |
| Hydrochloric Acid SCHEMBL1998577 | 0.73 | AVPR1A (0.48) | SIGMAR1NPY5RAVPR1ADHODHDRD2 | |
| SCHEMBL20977962 | 0.72 | SIGMAR1 (0.35) | SIGMAR1NPY5RAVPR1ADHODHDRD2 | |
| SCHEMBL171980 | 0.67 | SIGMAR1 (0.54) | SIGMAR1NPY5RAVPR1A | |
| SCHEMBL29674557 | 0.67 | SIGMAR1 (0.54) | SIGMAR1NPY5RAVPR1A | |
| SCHEMBL737225 | 0.67 | HRH3 (0.46) | SIGMAR1NPY5RDRD2HTR2C | |
| Hydrochloric Acid SCHEMBL2002554 | 0.66 | SIGMAR1 (0.52) | SIGMAR1NPY5RAVPR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138206-B2 | Piperidine derivative | MSD. K.K. (JP) | 2012-03-20 | — | — | US | disclosed |
| US-20090137576-A1 | Novel Piperidine Derivative | MSD K.K. (JP) | 2009-05-28 | — | — | US | disclosed |
| EP-1892241-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137576-A1 | Novel Piperidine Derivative | HRH4, HRH3, HRH1 | SIGMAR1 11/4885NPY5R 385/4885AVPR1A 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.