Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 5/20 | 0.76 |
| ▸ | PPIB | P23284 | 2/20 | 0.57 |
| ▸ | PPIG | Q13427 | 2/20 | 0.57 |
| ▸ | PPIA | P62937 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643825 | 0.87 | PPID (1.00) | PPIDPPIBPPIGPPIAMAPT | |
| Methylamine SCHEMBL8528191 | 0.83 | PPID (0.91) | PPIDPPIBPPIGPPIAMAPT | |
| SCHEMBL13745387 | 0.82 | PPID (0.55) | PPIDMAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL30078575 | 0.79 | PPID (0.55) | PPIDSMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL75205 | 0.79 | PPID (0.69) | PPIDPPIBPPIGPPIAMAPT | |
| Hydrochloric Acid SCHEMBL3926946 | 0.77 | PPID (0.68) | PPIDPPIBPPIGPPIAMAPT | |
| SCHEMBL2087667 | 0.77 | PPID (0.68) | PPIDMAPTNAMPTSMN1; SMN2LMNA | |
| SCHEMBL2034522 | 0.77 | PPID (0.76) | PPIDPPIBPPIGPPIASMN1; SMN2 | |
| SCHEMBL1557290 | 0.75 | PPID (0.64) | PPIDPPIBPPIGPPIAMAPT | |
| SCHEMBL1285009 | 0.75 | PPID (0.64) | PPIDPPIBPPIGPPIAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056593-A2 | α-HELIX MIMETICS AND METHOD RELATING TO THE TREATMENT OF CANCER STEM CELLS | CHOONGWAE PHARMA CORPORATION (KR) | 2007-05-18 | — | — | WO | disclosed |