SCHEMBL13745387

SCHEMBL13745387

CC(C)(C)OC(=O)CNNC(=O)NCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA7 P43166 1/20 0.46
CA14 Q9ULX7 1/20 0.46
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
RIPK1 Q13546 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
EPHX1 P07099 1/20 0.44
LMNA P02545 1/20 0.43
RAB9A P51151 1/20 0.43
CFD P00746 1/20 0.43
PTPN1 P18031 1/20 0.43
CTSK P43235 2/20 0.43
TP53 P04637 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6988810 0.88 PPID (0.68) PPIDSMN1; SMN2ALDH1A1MAPTCA12
SCHEMBL14531019 0.82 PPID (0.76) PPIDSMN1; SMN2ALDH1A1MAPTKDM4E
SCHEMBL4193438 0.81 CA12 (0.56) PPIDSMN1; SMN2ALDH1A1MAPTCA12
SCHEMBL14719815 0.80 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1KDM4EGAAL3MBTL1
SCHEMBL734928 0.79 ATM (0.55) PPIDSMN1; SMN2ALDH1A1CA12CA1
SCHEMBL14535782 0.79 SYK (0.52) SMN1; SMN2ALDH1A1MAPTCA12CA1
SCHEMBL14255755 0.79 EPHX1 (0.56) PPIDSMN1; SMN2ALDH1A1MAPTCA12
SCHEMBL28872153 0.78 GAA (0.53) PPIDSMN1; SMN2CA12CA1CA7
Hydrochloric Acid SCHEMBL6433307 0.78 ATM (0.53) PPIDSMN1; SMN2ALDH1A1MAPTCA12
SCHEMBL4256140 0.76 PPID (0.46) PPIDSMN1; SMN2CA12CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545683-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2026-02-10 US disclosed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 US disclosed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 US disclosed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 US disclosed
CN-115835865-A CBP/catenin signal transmission path inhibitor and application thereof 3+2 制药有限责任公司 2023-03-21 CN disclosed
EP-4117663-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 Pharma LLC (US) 2023-01-18 EP disclosed
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA, LLC 2021-10-14 US disclosed
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA, LLC 2021-10-14 US disclosed
WO-2021183796-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA (US) 2021-09-16 WO disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 US disclosed
WO-2007139346-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2007-12-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 PPID 2280/4885SMN1; SMN2 4342/4885ALDH1A1 2132/4885
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 PPID 975/4885SMN1; SMN2 103/4885ALDH1A1 648/4885
US-12545683-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, CTNNB1 PPID 3408/4885SMN1; SMN2 3429/4885ALDH1A1 2182/4885
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, EP300 PPID 2280/4885SMN1; SMN2 4342/4885ALDH1A1 2132/4885
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 PPID 2280/4885SMN1; SMN2 4342/4885ALDH1A1 2132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.