SCHEMBL75205

SCHEMBL75205

CCOC(=O)CNCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPID Q08752 3/20 0.69
SMN1; SMN2 Q16637 2/20 0.62
LTA4H P09960 4/20 0.58
PPIB P23284 1/20 0.50
PPIA P62937 1/20 0.50
PPIG Q13427 1/20 0.50
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.48
HTT P42858 1/20 0.48
NAMPT P43490 1/20 0.47
RECQL P46063 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3926946 0.98 PPID (0.68) PPIDSMN1; SMN2LTA4HPPIBPPIA
SCHEMBL12559711 0.92 PPID (0.64) PPIDSMN1; SMN2LTA4HPPIBPPIA
SCHEMBL12894961 0.91 PPID (0.58) PPIDSMN1; SMN2LTA4HPPIBPPIA
SCHEMBL1222472 0.88 LTA4H (0.57) PPIDSMN1; SMN2LTA4HPPIBPPIA
SCHEMBL548 0.87 LTA4H (0.64) PPIDSMN1; SMN2LTA4HALDH1A1
SCHEMBL11187635 0.86 PPID (0.54) PPIDSMN1; SMN2LTA4HPPIBPPIA
SCHEMBL8252663 0.86 SMN1; SMN2 (0.54) PPIDSMN1; SMN2LTA4HPPIBPPIA
SCHEMBL6518216 0.85 PPID (0.59) PPIDSMN1; SMN2LTA4HALDH1A1
SCHEMBL5369633 0.84 ALDH1A1 (0.59) PPIDALDH1A1RECQL
SCHEMBL8495474 0.84 LTA4H (0.55) PPIDSMN1; SMN2LTA4HALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060063-A Preparation method of 2-oxa-7-azaspiro [3.4] octane-6-carboxylic acid and derivatives thereof 南京富润凯德生物医药有限公司 2024-12-03 CN claimed
CN-116903505-A Method for synthesizing S-biaryl dithio carbamate compound 华南理工大学 2023-10-20 CN claimed
CN-114072486-B Alkaline ashless additive and lubricating composition containing said additive 路博润公司 2023-06-09 CN claimed
CN-111620877-B Process for preparing 1-benzyl-5- (tert-butyloxycarbonyl) octahydropyrrolopyrrole-2-carboxylic acid 无锡合全药业有限公司 2022-05-17 CN claimed
CN-114230781-A Preparation method of low molecular weight polycarbonate polyether polyol with autocatalysis effect 河北工业大学 2022-03-25 CN claimed
CN-110734393-B Preparation method of N-benzyl-3-oxopiperidine-4-carboxylic acid ethyl ester hydrochloride 南京恒远科技开发有限公司 2022-02-25 CN claimed
CN-114072486-A Basic ashless additives and lubricating compositions containing said additives 路博润公司 2022-02-18 CN claimed
CN-111620877-A Process for preparing 1-benzyl-5- (tert-butyloxycarbonyl) octahydropyrrolopyrrole-2-carboxylic acid 无锡合全药业有限公司 2020-09-04 CN claimed
CN-110981658-A Safe smokeless and sulfur-free firecracker and firecracker nitrate medicament and preparation method thereof 江西吉润花炮新材料科技有限公司 2020-04-10 CN claimed
CN-110734393-A Preparation method of N-benzyl-3-oxopiperidine-4-carboxylic acid ethyl ester hydrochloride 南京恒远科技开发有限公司 2020-01-31 CN claimed
US-20150056265-A1 COATING COMPOSITION AND MEDICAL DEVICE TERUMO KABUSHIKI KAISHA (JP) 2015-02-26 US claimed
EP-2813250-A1 COATING COMPOSITION AND MEDICAL DEVICE Terumo Kabushiki Kaisha (JP) 2014-12-17 EP claimed
CN-104203297-A Coating composition and medical device TERUMO CORP 2014-12-10 CN claimed
CN-101896479-B Process for the preparation of pyrido [2,1-a] isoquinoline derivatives HOFFMANN LA ROCHE 2013-08-07 CN claimed
EP-2234997-B1 PROCESS FOR THE PREPARATION OF PYRIDO[2,1-A]ISOQUINOLINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2012-09-05 EP claimed
CN-101896479-A Process for the preparation of pyrido [2,1-a] isoquinoline derivatives HOFFMANN LA ROCHE 2010-11-24 CN claimed
CN-1202076-C Production method of N-benzyl glycine ethyl ester DONGCHANG CHEMICAL CO LTD NANT (CN) 2005-05-18 CN claimed
CN-1477095-A Production method of N-benzyl glycine ethyl ester 南通市东昌化工有限公司 2004-02-25 CN claimed
EP-0492136-A2 Retroviral protease inhibitors derived from 3-chloro-2-chloromethyl-1-propene AMERICAN CYANAMID COMPANY (US) 1992-07-01 EP claimed
EP-0230151-A2 Cholecystokinin antagonists BIOMEASURE, INC. (US) 1987-07-29 EP claimed