Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926356 | 0.86 | LMNA (0.56) | KMOSMN1; SMN2LMNAALDH1A1PTAFR | |
| SCHEMBL16014666 | 0.75 | LMNA (0.60) | KMOSMN1; SMN2LMNANPSR1GAA | |
| SCHEMBL926841 | 0.75 | SMN1; SMN2 (0.47) | KMOSMN1; SMN2LMNAHIF1ANPSR1 | |
| SCHEMBL1531360 | 0.72 | KDM4E (0.49) | SMN1; SMN2LMNAHIF1AGAAALDH1A1 | |
| SCHEMBL30147353 | 0.71 | HSD11B1 (0.61) | KMOSMN1; SMN2LMNAPOLBALDH1A1 | |
| SCHEMBL13225994 | 0.69 | LMNA (0.47) | SMN1; SMN2LMNAHIF1ANPSR1RXFP1 | |
| SCHEMBL17359685 | 0.68 | SMN1; SMN2 (0.50) | KMOSMN1; SMN2HIF1ANPSR1RXFP1 | |
| SCHEMBL1531265 | 0.68 | LMNA (0.50) | SMN1; SMN2LMNANPSR1ALDH1A1MAPT | |
| SCHEMBL4005594 | 0.67 | LMNA (0.47) | SMN1; SMN2LMNAHIF1AALDH1A1MAPT | |
| SCHEMBL18755021 | 0.67 | SMN1; SMN2 (0.36) | KMOSMN1; SMN2LMNAHIF1ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007060026-A1 | UREA DERIVATIVES USEFUL AS CALCIUM RECEPTOR MODULATORS | GALAPAGOS SAS (FR) | 2007-05-31 | — | — | WO | disclosed |