Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6055146 | 0.83 | PDE2A (0.43) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL20342536 | 0.83 | PDE2A (0.43) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL8422202 | 0.82 | TP53 (0.40) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL6055266 | 0.80 | PDE5A (0.40) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL12630806 | 0.79 | SLC6A2 (0.41) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL6055394 | 0.79 | PDE5A (0.46) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL9082794 | 0.79 | TP53 (0.38) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL9685032 | 0.78 | TDP1 (0.48) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL8756974 | 0.78 | TDP1 (0.48) | TP53TDP1TRPA1LMNACHRM1 | |
| SCHEMBL16071368 | 0.77 | PDE5A (0.51) | TP53TDP1TRPA1LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056469-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |