Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 2/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.62 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.61 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.55 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115373 | 1.00 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL13777726 | 1.00 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL2749577 | 1.00 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL13296262 | 1.00 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL10459063 | 0.91 | ADORA2A (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL15462103 | 0.87 | ADORA3 (0.77) | AHCYADORA3HSP90B1ADORA2AADORA2B | |
| SCHEMBL19423461 | 0.87 | ADORA3 (0.77) | AHCYADORA3HSP90B1ADORA2AADORA2B | |
| SCHEMBL12359604 | 0.86 | ADORA2A (0.57) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL30712751 | 0.86 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL9404167 | 0.86 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214665-B2 | 2-propynyl adenosine analogs having A2A agonist activity and compositions thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2007-05-08 | — | — | US | disclosed |