Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417082 | 0.76 | CHRNB4 (0.39) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL8703745 | 0.73 | CHRNB4 (0.37) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL13372443 | 0.73 | HTR2C (0.46) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL18883053 | 0.73 | HTR2C (0.46) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL793625 | 0.73 | CHRNB4 (0.37) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL131253 | 0.73 | CHRNB4 (0.37) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL5541645 | 0.73 | CHRNB4 (0.37) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL5749290 | 0.73 | HTR2C (0.46) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL548964 | 0.73 | HTR2C (0.46) | CHRNB4CHRNA3MEN1KMT2AGAA | |
| SCHEMBL13323694 | 0.73 | CHRNB4 (0.37) | CHRNB4CHRNA3MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11241431-B2 | N-substituted indole derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-02-08 | — | — | US | disclosed |
| US-20200289507-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2020-09-17 | — | — | US | disclosed |
| US-20070105862-A1 | Heat-shock protein binders | ABBOTT LABORATORIES | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200289507-A1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | PTGER1, PTGER4, PTGER2 | CHRNB4 307/4885CHRNA3 385/4885MEN1 2595/4885 |
| US-20070105862-A1 | Heat-shock protein binders | HSP90AB1, HSP90AB2P, HSP90B1 | CHRNB4 4404/4885CHRNA3 4648/4885MEN1 4017/4885 |
| US-11241431-B2 | N-substituted indole derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | CHRNB4 307/4885CHRNA3 385/4885MEN1 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.