Sugi Predict

Sugi Predict / Compounds / SCHEMBL548964

SCHEMBL548964

SCHEMBL548964

CC1CNc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ HTR2C P28335 2/20 0.46
▸ HTR2A P28223 1/20 0.46
▸ HTR2B P41595 1/20 0.46
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CHRNB4 P30926 1/20 0.37
▸ CHRNA3 P32297 1/20 0.37
▸ HTR5A P47898 2/20 0.36
▸ MAPT P10636 2/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ PAX8 Q06710 1/20 0.35
▸ GAA P10253 1/20 0.34
▸ AR P10275 1/20 0.33
▸ BRD4 O60885 1/20 0.33
▸ CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5749290 1.00 HTR2C (0.46) HTR2CHTR2AHTR2BCA1CA2
SCHEMBL18883053 1.00 HTR2C (0.46) HTR2CHTR2AHTR2BCA1CA2
SCHEMBL13372443 1.00 HTR2C (0.46) HTR2CHTR2AHTR2BCA1CA2
Hydrochloric Acid SCHEMBL13387451 0.98 HTR2C (0.44) HTR2CHTR2AHTR2BCA1CA2
Hydrochloric Acid SCHEMBL30259584 0.98 HTR2C (0.44) HTR2CHTR2AHTR2BCA1CA2
Formic Acid SCHEMBL28476115 0.89 HTR2C (0.39) HTR2CHTR2AHTR2BCA1CA2
SCHEMBL10671019 0.81 ALDH1A1 (0.39) HTR2CHTR2AHTR2BCA1CA2
SCHEMBL15108157 0.78 HTR2C (0.43) HTR2CHTR2AHTR2BCA1CA2
SCHEMBL12350365 0.78 HTR2C (0.39) HTR2CHTR2AHTR2BHTR5AMEN1
SCHEMBL4433763 0.78 HTR2C (0.39) HTR2CHTR2AHTR2BHTR5AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115863-A1 FUEL COMPOSITION COMPRISING A RENEWABLE BASE AND A NITROGEN-CONTAINING HETEROCYCLIC AROMATIC COMPOUND TOTALENERGIES ONETECH (FR) 2024-06-06 — — WO claimed
CN-113671078-B Sepsis prognosis model establishing method based on metabonomics 郑州大学第一附属医院 2023-03-03 — — CN claimed
CN-113321675-B Chiral 3-methylene indoline compound and preparation method thereof 西华师范大学 2022-07-01 — — CN claimed
CN-113321675-A Chiral 3-methylene indoline compound and preparation method thereof 西华师范大学 2021-08-31 — — CN claimed
CN-109161028-B Preparation method of photodegradable two-dimensional polymer with cucurbituril as structural unit 四川大学 2020-12-08 — — CN claimed
US-6455570-B1 SUBSTITUTED POLYPYRROLIDONE COMPOUND, USEFUL FOR TREATMENT OF INFLAMMATORY NEOPLASTIC AND DEGENERATIVE DISEASES THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2002-09-24 — — US claimed
US-20020123635-A1 Polypyrrolinone based inhibitors of matrix metalloproteases NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-09-05 — — US claimed
JP-63185959-A — — None — — JP disclosed
JP-58170754-A — — None — — JP disclosed
US-20260125349-A1 PROCESS FOR THE FLUORINATION AND/OR CYCLIZATION OF AN AMINO ALKENE OR ALKYNE IN A CONTINUOUS STREAM AND FACILITY FOR PERFORMING THE PROCESS UNIV POITIERS (FR) 2026-05-07 — — US disclosed
US-12612424-B2 HPK1 inhibitors and uses thereof REGOR PHARMACEUTICALS, INC. (US) 2026-04-28 — — US disclosed
EP-4692071-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS TOKUYAMA CORPORATION (JP) 2026-02-11 — — EP disclosed
EP-4598903-A1 PROCESS FOR THE FLUORINATION AND/OR CYCLIZATION OF AN AMINO ALKENE OR ALKYNE IN A CONTINUOUS STREAM AND FACILITY FOR PERFORMING THE PROCESS Université de Poitiers (FR) 2025-08-13 — — EP disclosed
US-4515949-A [2-(1H-indol-1-yl)ethyl]-2-piperazine and pyrido[1,2-a]indol-9-one as intermediates for pyrazino(2,3-3,4)pyrido(1,2-a) indoles which are useful for treating hypertension in mammals AMERICAN HOME PRODUCTS CORPORATION (US) 1985-05-07 — — US disclosed
US-4482714-A Pyrazino[2',3'-3,4]pyrido[1,2-a]indole derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1984-11-13 — — US disclosed
EP-0115920-A2 Pyrazino(2',3'-3,4)pyrido(1,2-a) indole derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1984-08-15 — — EP disclosed
JP-S58170754-A PREPARATION OF INDOLINE COMPOUND KIKUKAWA YASUO 1983-10-07 — — JP disclosed
US-4290870-A 5-ISOXOLONE, AROMATIC CARBONYL, DIALKYLAMINO AROMATIC CARBONYL OR FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 — — US disclosed
US-4159271-A CYCLIZATION OF A 2-HALOGENOPHENETHYLAMINE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1979-06-26 — — US disclosed
US-3935199-A ANALEPTIC MEAD JOHNSON & COMPANY (US) 1976-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612424-B2 HPK1 inhibitors and uses thereof NEK11, NEK1, CSNK1A1 HTR2C 2173/4885HTR2A 2117/4885HTR2B 2600/4885
US-20260125349-A1 PROCESS FOR THE FLUORINATION AND/OR CYCLIZATION OF AN AMINO ALKENE OR ALKYNE IN A CONTINUOUS STREAM AND FACILITY FOR PERFORMING THE PROCESS FIBP, FGB, SUB1 HTR2C 456/4885HTR2A 588/4885HTR2B 246/4885
US-20020123635-A1 Polypyrrolinone based inhibitors of matrix metalloproteases MMP9, MMP16, MMP3 HTR2C 4844/4885HTR2A 4599/4885HTR2B 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.