Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703745 | 1.00 | CHRNB4 (0.37) | CHRNB4CHRNA3PARP3PAX8MEN1 | |
| SCHEMBL29636531 | 1.00 | CHRNB4 (0.37) | CHRNB4CHRNA3PARP3PAX8MEN1 | |
| SCHEMBL30290030 | 0.78 | F12 (0.36) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL2172550 | 0.78 | F12 (0.36) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL4207481 | 0.78 | PARP3 (0.40) | CHRNB4CHRNA3PARP3PAX8MEN1 | |
| SCHEMBL224810 | 0.78 | F12 (0.36) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL2172225 | 0.78 | F12 (0.36) | MEN1GAAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27979283 | 0.77 | ALDH1A1 (0.37) | MEN1GAAKMT2AALDH1A1 | |
| SCHEMBL30417082 | 0.76 | CHRNB4 (0.39) | CHRNB4CHRNA3PARP3PAX8MEN1 | |
| Ethane SCHEMBL11061598 | 0.75 | BCHE (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825686-A | Oxazepino [3,2-b ] indole compound and synthetic method thereof | 贵州医科大学 | 2020-10-27 | — | — | CN | claimed |
| US-20170281805-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES | MAHESHWARI DIVYA (IN) | 2017-10-05 | — | — | US | claimed |
| EP-3200779-A2 | NOVEL ANTHRANILIC ACID DERIVATIVES | Maheshwari, Divya (IN) | 2017-08-09 | — | — | EP | claimed |
| EP-2621902-B1 | 3-AZABICYCLO[3.1.0]HEXANE COMPOUNDS USEFUL FOR THE TREATMENT OF CNS DISORDERS | PANACEA BIOTEC LTD (IN) | 2017-04-12 | — | — | EP | claimed |
| CN-104744476-B | IMIDAZOPYRAZINE Syk INHIBITORS | 吉利德康涅狄格公司 | 2017-04-12 | — | — | CN | claimed |
| WO-2016051306-A2 | NOVEL ANTHRANILIC ACID DERIVATIVES | MAHESHWARI DIVYA (IN) | 2016-04-07 | — | — | WO | claimed |
| US-20150218155-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-08-06 | — | — | US | claimed |
| EP-2748164-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS | Merck Patent GmbH (DE) | 2014-07-02 | — | — | EP | claimed |
| US-8455479-B2 | Heterocyclic compounds | PANACEA BIOTEC LIMITED (IN) | 2013-06-04 | — | — | US | claimed |
| WO-2013026516-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | WO | claimed |
| US-20130029944-A1 | INHIBITORS OF PROTEIN KINASES | PORTOLA PHARMACEUTICALS, INC. (US) | 2013-01-31 | — | — | US | claimed |
| EP-2271631-A2 | INHIBITORS OF PROTEIN KINASES | Portola Pharmaceuticals, Inc. (US) | 2011-01-12 | — | — | EP | claimed |
| WO-2009131687-A2 | INHIBITORS OF PROTEIN KINASES | PORTOLA PHARMACEUTICALS, INC. (US) | 2009-10-29 | — | — | WO | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| US-20250090540-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | RELAY THERAPEUTICS, INC. | 2025-03-20 | — | — | US | disclosed |
| EP-4399196-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | Relay Therapeutics, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| EP-1489540-A1 | INFORMATION PROVIDING SYSTEM AND PAPER-SHAPED DISPLAY MEDIUM | DAI NIPPON PRINTING CO., LTD. (JP) | 2004-12-22 | — | — | EP | disclosed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281805-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES | SLC47A1, ABCC1, ABCB1 | CHRNB4 3747/4885CHRNA3 4161/4885PARP3 2102/4885 |
| US-20150218155-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS | CDK1, CDK2, CDK4 | CHRNB4 2086/4885CHRNA3 1735/4885PARP3 555/4885 |
| US-20130029944-A1 | INHIBITORS OF PROTEIN KINASES | SYK, BTK, JAK2 | CHRNB4 4884/4885CHRNA3 4876/4885PARP3 1247/4885 |
| US-20250090540-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF USE THEREOF | PIK3CA, PIK3CB, PIK3CD | CHRNB4 3970/4885CHRNA3 3914/4885PARP3 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.