Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027356 | 0.79 | NCF1 (0.37) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL12535970 | 0.77 | NCF1 (0.35) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL4594598 | 0.76 | NCF1 (0.43) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL12617396 | 0.75 | ACE (0.40) | GNAI3GNAO1GNAI1CACNA2D1CACNA1B | |
| SCHEMBL12593604 | 0.74 | NCF1 (0.39) | NCF1GNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL12535764 | 0.72 | NCF1 (0.38) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL4596098 | 0.71 | TP53 (0.56) | NCF1GNAI3GNAO1GNAI1CACNA2D1 | |
| SCHEMBL20041835 | 0.69 | NCF1 (0.35) | NCF1GNAI3GNAO1GNAI1 | |
| SCHEMBL12535758 | 0.68 | NCF1 (0.34) | NCF1GNAI3GNAO1GNAI1CACNA1C | |
| SCHEMBL13890712 | 0.68 | NCF1 (0.31) | NCF1GNAI3GNAO1GNAI1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787992-A1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-05-23 | — | — | EP | disclosed |