Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041835 | 0.89 | NCF1 (0.35) | NCF1GNAI3GNAO1GNAI1TACR2 | |
| SCHEMBL12535970 | 0.85 | NCF1 (0.35) | NCF1GNAI3GNAO1GNAI1HRH4 | |
| SCHEMBL12535764 | 0.84 | NCF1 (0.38) | NCF1GNAI3GNAO1GNAI1HRH4 | |
| SCHEMBL7876684 | 0.84 | — | — | |
| SCHEMBL4594598 | 0.83 | NCF1 (0.43) | NCF1GNAI3GNAO1GNAI1HRH4 | |
| SCHEMBL12593604 | 0.82 | NCF1 (0.39) | NCF1GNAI3GNAO1GNAI1HRH4 | |
| SCHEMBL11892780 | 0.79 | TP53 (0.50) | — | |
| SCHEMBL12134648 | 0.79 | — | — | |
| SCHEMBL1665955 | 0.79 | TP53 (0.50) | — | |
| SCHEMBL11892781 | 0.79 | TP53 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673348-A2 | BENZOIMIDAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005044807-A2 | BENZOIMIDAZOLE COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-05-19 | — | — | WO | disclosed |