Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705208 | 0.83 | MAPT (0.68) | MAPTPDE4BNPC1RAB9AMMP1 | |
| SCHEMBL25545442 | 0.81 | MAPT (0.62) | TAS1R3TAS1R1MAPTPDE4BNPC1 | |
| SCHEMBL16552644 | 0.80 | MMP1 (0.76) | MAPTPDE4BNPC1RAB9AMMP1 | |
| SCHEMBL4530719 | 0.80 | PDE4B (0.72) | MAPTPDE4BNPC1RAB9AMMP1 | |
| SCHEMBL20056122 | 0.80 | L3MBTL1 (0.53) | MAPTNPC1RAB9AHDAC1HDAC8 | |
| SCHEMBL5111949 | 0.79 | MAPT (0.58) | TAS1R3TAS1R1MAPTPDE4BNPC1 | |
| SCHEMBL1304627 | 0.78 | PDE4B (0.70) | MAPTPDE4BNPC1RAB9AMMP1 | |
| SCHEMBL10745082 | 0.77 | MAPT (0.53) | TAS1R3TAS1R1MAPTPDE4BNPC1 | |
| SCHEMBL10745086 | 0.77 | MAPT (0.53) | TAS1R3TAS1R1MAPTPDE4BNPC1 | |
| SCHEMBL4082864 | 0.77 | PDE4B (0.86) | MAPTPDE4BNPC1RAB9AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1787992-A1 | Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-05-23 | — | — | EP | disclosed |