Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2186229 | 0.85 | MAPT (0.50) | MAPTTHRBLIPGKMT2AGAA | |
| SCHEMBL13805554 | 0.84 | CNR2 (0.52) | MAPTTHRBKMT2AGAAHPGD | |
| SCHEMBL13793202 | 0.83 | LMNA (0.57) | MAPTTHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL92997 | 0.79 | CNR2 (0.51) | MAPTTHRBLIPGKMT2AGAA | |
| SCHEMBL83038 | 0.78 | LMNA (0.58) | MAPTTHRBLIPGKMT2ARXFP1 | |
| SCHEMBL92988 | 0.78 | KMT2A (0.52) | MAPTLIPGKMT2AGAARXFP1 | |
| SCHEMBL1503237 | 0.76 | KMT2A (0.45) | MAPTTHRBLIPGKMT2AGAA | |
| SCHEMBL12516721 | 0.76 | MAPT (0.46) | MAPTTHRBKMT2AGAARXFP1 | |
| SCHEMBL80877 | 0.76 | LMNA (0.61) | MAPTKMT2AGAARXFP1KDM4E | |
| SCHEMBL92995 | 0.75 | CNR2 (0.52) | MAPTTHRBLIPGGAARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790638-A1 | CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | Shionogi Co., Ltd. (JP) | 2007-05-30 | — | — | EP | disclosed |