Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14138215 | 0.89 | CNR2 (0.52) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL12697368 | 0.82 | FAAH (0.61) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL8981479 | 0.81 | CNR2 (0.55) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL12697309 | 0.79 | FAAH (0.57) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL8981503 | 0.78 | CNR2 (0.54) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL13805556 | 0.78 | CNR2 (0.53) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL8981509 | 0.78 | CNR2 (0.53) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL12697379 | 0.78 | CNR2 (0.65) | CNR2FAAHHPGDMAPTHTT | |
| SCHEMBL13805554 | 0.77 | CNR2 (0.52) | CNR2FAAHHPGDGAAMAPT | |
| SCHEMBL8981574 | 0.77 | CNR2 (0.52) | CNR2FAAHHPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790638-A1 | CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | Shionogi Co., Ltd. (JP) | 2007-05-30 | — | — | EP | disclosed |