Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352556 | 0.89 | UCHL1 (0.62) | UCHL1USP30SMN1; SMN2KDM4ERECQL | |
| SCHEMBL10282902 | 0.86 | SMN1; SMN2 (0.68) | UCHL1USP30SMN1; SMN2KDM4ERECQL | |
| SCHEMBL14132463 | 0.86 | SMN1; SMN2 (0.73) | UCHL1USP30SMN1; SMN2KDM4ERECQL | |
| SCHEMBL14132621 | 0.84 | SMN1; SMN2 (0.71) | UCHL1USP30SMN1; SMN2KDM4ERECQL | |
| SCHEMBL23806536 | 0.84 | SMN1; SMN2 (0.71) | UCHL1USP30SMN1; SMN2KDM4ERECQL | |
| SCHEMBL14842518 | 0.83 | KDM4E (0.58) | SMN1; SMN2KDM4ERECQLALDH1A1CYP3A4 | |
| SCHEMBL24477877 | 0.83 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4ERECQLALDH1A1CYP3A4 | |
| SCHEMBL10124067 | 0.83 | ALDH1A1 (0.71) | SMN1; SMN2KDM4ERECQLALDH1A1CYP3A4 | |
| SCHEMBL20082404 | 0.82 | UCHL1 (0.55) | UCHL1USP30SMN1; SMN2KDM4ERECQL | |
| SCHEMBL14923992 | 0.81 | USP30 (0.64) | UCHL1USP30SMN1; SMN2KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011047319-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |