SCHEMBL14537780

SCHEMBL14537780

CC[C@]12COC(C(n3cnc4c(=O)[nH]c(N)nc43)O1)[C@H]2OC

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 1/20 0.46
▸ HINT1 P49773 3/20 0.45
▸ STING1 Q86WV6 9/20 0.43
▸ PDE3B Q13370 1/20 0.43
▸ PDE3A Q14432 1/20 0.43
▸ ADORA3 P0DMS8 1/20 0.42
▸ NT5E P21589 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14512779 1.00 HPGD (0.46) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL16587630 0.93 HPGD (0.44) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL12646749 0.92 HPGD (0.45) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL12015165 0.92 HPGD (0.45) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL12590101 0.92 HPGD (0.45) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL24263984 0.92 HPGD (0.45) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL19840285 0.92 HPGD (0.45) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL18058960 0.91 HPGD (0.44) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL24429201 0.91 HPGD (0.44) HPGDHINT1STING1PDE3BPDE3A
SCHEMBL27277340 0.89 HPGD (0.43) HPGDHINT1STING1PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070117773-A1 Telomerase-inhibiting ENA oligonucleotide SANKYO COMPANY, LIMITED (JP) 2007-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070117773-A1 Telomerase-inhibiting ENA oligonucleotide TERT, ENO1, TERB1 HPGD 2529/4885HINT1 4064/4885STING1 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback