Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16362200 | 0.82 | SMN1; SMN2 (0.52) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL13478231 | 0.79 | THRA (0.41) | TSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30967302 | 0.79 | HPGD (0.39) | HPGDRAB9AHTTMEN1KMT2A | |
| SCHEMBL30967300 | 0.79 | HPGD (0.39) | HPGDRAB9AHTTMEN1KMT2A | |
| SCHEMBL13851975 | 0.78 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL941194 | 0.78 | DRD2 (0.40) | SMN1; SMN2RAB9ANPC1TSHRKDM4E | |
| SCHEMBL12264984 | 0.78 | SMN1; SMN2 (0.49) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL1459228 | 0.77 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL14511752 | 0.77 | SLC6A4 (0.52) | SMN1; SMN2LMNARAB9AHTTCYP1A2 | |
| SCHEMBL13210257 | 0.77 | ESR1 (0.41) | KDM4EMAPTESR1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |