Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 16/20 | 0.75 |
| ▸ | AURKB | Q96GD4 | 11/20 | 0.75 |
| ▸ | LCK | P06239 | 8/20 | 0.75 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14538620 | 0.88 | PTK6 (0.59) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL8239898 | 0.84 | AURKB (0.59) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL14387555 | 0.84 | MAPKAPK5 (0.65) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL13954861 | 0.83 | AURKB (0.56) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL14387502 | 0.81 | MAPKAPK5 (0.62) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL14536960 | 0.79 | MAPKAPK5 (0.62) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL13954946 | 0.78 | PTK6 (0.53) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL13954945 | 0.78 | PTK6 (0.53) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL30138985 | 0.77 | MAPKAPK5 (0.62) | PTK6AURKBLCKMAPKAPK5AURKA | |
| SCHEMBL14537083 | 0.76 | PTK6 (0.56) | PTK6AURKBLCKMAPKAPK5AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058942-A2 | IMIDAZOPYRAZINES AS PROTEIN KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-05-24 | — | — | WO | disclosed |