SCHEMBL145386

SCHEMBL145386

CCCCCCC1OC1C1=CC2CCC1C2

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
CYP1A2 P05177 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SPHK1 Q9NYA1 5/20 0.31
SPHK2 Q9NRA0 4/20 0.31
POLB P06746 1/20 0.31
FASN P49327 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8372323 0.67 SPHK1 (0.41) ALDH1A1SPHK1SPHK2
SCHEMBL1011862 0.67 SPHK1 (0.41) ALDH1A1SPHK1SPHK2
SCHEMBL155523 0.67 SPHK1 (0.41) ALDH1A1SPHK1SPHK2
SCHEMBL153537 0.67 SPHK1 (0.41) ALDH1A1SPHK1SPHK2
SCHEMBL152342 0.67 SPHK1 (0.41) ALDH1A1SPHK1SPHK2
SCHEMBL5898950 0.67 SPHK1 (0.41) ALDH1A1SPHK1SPHK2
SCHEMBL379440 0.65 CFTR (0.45) POLBFASN
SCHEMBL4624725 0.65 CFTR (0.45) POLBFASN
SCHEMBL797512 0.65 SPHK1 (0.38) SPHK1SPHK2
SCHEMBL1499434 0.65 CFTR (0.45) POLBFASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9647222-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9647213-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9583713-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
EP-2676979-B1 Gate insulator layer for electronic devices MERCK PATENT GMBH (DE) 2016-07-13 EP disclosed
US-20150372246-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES FLEXENABLE TECHNOLOGY LIMITED (GB) 2015-12-24 US disclosed
US-20150349263-A1 INTERLAYER FOR ELECTRONIC DEVICES FLEXENABLE TECHNOLOGY LIMITED (GB) 2015-12-03 US disclosed
EP-2611842-B1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-11-04 EP disclosed
US-9175123-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
EP-2611841-B1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-10-28 EP disclosed
EP-2676978-B1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-24 EP disclosed
EP-2676979-A1 Gate insulator layer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2676978-A1 Interlayer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2611841-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
EP-2611842-A1 INTERLAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
US-20120056249-A1 INTERLAYER FOR ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
WO-2012028278-A1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
WO-2012028279-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
US-20120056183-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed