Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8280136 | 0.85 | ROCK2 (0.45) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL586725 | 0.77 | TYR (0.48) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL330127 | 0.76 | TYR (0.47) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL1475441 | 0.74 | CSNK2A1 (0.59) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL1474762 | 0.73 | CSNK2A1 (0.56) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL12767914 | 0.72 | TYR (0.62) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL8225940 | 0.72 | NAMPT (0.50) | NAMPTHDAC1 | |
| SCHEMBL24590352 | 0.70 | TYR (0.67) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL1745407 | 0.70 | MEN1 (0.60) | TYRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL24590163 | 0.69 | MAPT (0.57) | TYRMAPTMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044893-A2 | COMPOUNDS AND METHODS FOR INHIBITING HEPATITIS C VIRAL REPLICATION | INTERMUNE, INC. (US) | 2007-04-19 | — | — | WO | disclosed |