Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 6/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29201353 | 0.86 | CHRM1 (0.48) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Acetic Acid SCHEMBL17186677 | 0.86 | CHRM5 (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Butyric Acid SCHEMBL144922 | 0.86 | FFAR3 (0.54) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Methoxyacetic Acid SCHEMBL17418335 | 0.85 | CHRM5 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Propionic Acid SCHEMBL147098 | 0.83 | BBOX1 (0.52) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Propionic Acid SCHEMBL142732 | 0.83 | BBOX1 (0.52) | CYP2C19ESR1MEN1RECQLKMT2A | |
| Valeric Acid SCHEMBL145879 | 0.83 | CA1 (0.55) | ADRA1AADRA2ALMNAMAPTBLM | |
| Bicarbonate SCHEMBL29201465 | 0.81 | CHRM1 (0.52) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Propionic Acid SCHEMBL144975 | 0.81 | CHRM5 (0.43) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Propionic Acid SCHEMBL142757 | 0.81 | CHRM2 (0.37) | CHRM1CHRM3CHRM2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058057-A1 | Anti-dandruff Agents | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | US | claimed |
| WO-2010136104-A2 | ANTI-DANDRUFF AGENTS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | claimed |
| US-20120058057-A1 | Anti-dandruff Agents | MERCK PATENT GMBH (DE) | 2012-03-08 | — | — | US | disclosed |
| WO-2010136104-A2 | ANTI-DANDRUFF AGENTS | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058057-A1 | Anti-dandruff Agents | POLR1C, ETF1, PIK3C3 | CHRM5 3597/4885CHRM1 2726/4885CHRM3 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.