Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KIFC1 | Q9BW19 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165451 | 0.89 | PPARG (0.52) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5165350 | 0.86 | L3MBTL1 (0.50) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5162953 | 0.86 | L3MBTL1 (0.50) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7183487 | 0.82 | L3MBTL1 (0.48) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14408258 | 0.81 | L3MBTL1 (0.45) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14408266 | 0.81 | L3MBTL1 (0.52) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14539768 | 0.79 | L3MBTL1 (0.52) | L3MBTL1KIFC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16481854 | 0.75 | L3MBTL1 (0.64) | L3MBTL1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL7294504 | 0.74 | L3MBTL1 (0.62) | L3MBTL1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5163666 | 0.74 | MAPK14 (0.47) | NPC1RAB9ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-B1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-04-11 | — | — | EP | disclosed |