Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KIFC1 | Q9BW19 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165451 | 0.92 | PPARG (0.52) | L3MBTL1FOLH1PPARGPPARANPC1 | |
| SCHEMBL5165350 | 0.83 | L3MBTL1 (0.50) | L3MBTL1NPC1RAB9AKIFC1LMNA | |
| SCHEMBL5162953 | 0.83 | L3MBTL1 (0.50) | L3MBTL1PPARGPPARANPC1RAB9A | |
| SCHEMBL14539769 | 0.82 | L3MBTL1 (0.49) | L3MBTL1PPARGPPARANPC1RAB9A | |
| SCHEMBL14539768 | 0.80 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AKIFC1LMNA | |
| SCHEMBL14408258 | 0.78 | L3MBTL1 (0.45) | L3MBTL1PPARGPPARANPC1RAB9A | |
| SCHEMBL14408266 | 0.78 | L3MBTL1 (0.52) | L3MBTL1NPC1RAB9AKIFC1LMNA | |
| SCHEMBL5165370 | 0.77 | L3MBTL1 (0.54) | L3MBTL1PPARANPC1RAB9ALMNA | |
| SCHEMBL557511 | 0.75 | CTRC (0.62) | FOLH1PPARGPPARAPTGESALOX5 | |
| SCHEMBL11474111 | 0.74 | ADCY6 (0.53) | FOLH1PPARGPPARAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |