Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APC | P25054 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540788 | 0.85 | EGFR (0.67) | EGFRERBB2PKMAPCNPSR1 | |
| SCHEMBL14541215 | 0.80 | ALDH1A1 (0.55) | EGFRERBB2PKMAPCMEN1 | |
| SCHEMBL14540795 | 0.77 | NPSR1 (0.73) | EGFRERBB2PKMAPCNPSR1 | |
| SCHEMBL23268983 | 0.73 | BCL2 (0.61) | MEN1KMT2A | |
| SCHEMBL14540796 | 0.72 | EGFR (0.68) | EGFRERBB2PKMAPCNPSR1 | |
| SCHEMBL14540882 | 0.67 | CA1 (0.81) | PKMNPSR1CA1CA2CA9 | |
| SCHEMBL14541107 | 0.66 | CA1 (0.68) | EGFRERBB2PKMAPCNPSR1 | |
| SCHEMBL14540883 | 0.65 | CA1 (0.78) | PKMNPSR1CA1CA2CA9 | |
| SCHEMBL14541083 | 0.63 | CA1 (0.74) | CA1CA2CA9MEN1KMT2A | |
| SCHEMBL14541217 | 0.63 | CA1 (0.74) | CA1CA2CA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038425-A2 | ANTI-VIRAL COMPOUINDS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-04-05 | — | — | WO | disclosed |