Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12411691 | 0.87 | EPHX2 (0.51) | MAPTLMNAMET | |
| SCHEMBL14540917 | 0.76 | CCNK (0.44) | KDM4EALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL14423725 | 0.74 | KDR (0.52) | MAPTLMNASYKMET | |
| SCHEMBL14609650 | 0.73 | CSF1R (0.49) | — | |
| SCHEMBL12459935 | 0.72 | CD274 (0.79) | KDM4EALDH1A1CYP2D6CYP2C9HTT | |
| SCHEMBL10163201 | 0.70 | RAF1 (0.63) | SCN9ALMNACD274MET | |
| SCHEMBL1895333 | 0.70 | BRD4 (0.45) | KDM4EALDH1A1MAPTCYP1A2GAA | |
| SCHEMBL617886 | 0.70 | CYP2C19 (0.71) | KDM4EALDH1A1POLBCYP2D6CYP1A2 | |
| SCHEMBL22823029 | 0.68 | SMN1; SMN2 (0.70) | KDM4EALDH1A1POLBCYP2D6CYP1A2 | |
| SCHEMBL30175940 | 0.68 | KDM4E (0.87) | KDM4EALDH1A1MAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-A1 | Process for the preparation of 4-phenoxy quinoline derivatives | Eisai R&D Management Co., Ltd. (JP) | 2007-04-25 | — | — | EP | disclosed |