Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4572822 | 0.93 | CYP2C19 (0.69) | SMN1; SMN2ALDH1A1KDM4ECYP2C9CYP2D6 | |
| Hydrochloric Acid SCHEMBL7398448 | 0.91 | CYP2C19 (0.67) | SMN1; SMN2ALDH1A1KDM4ECYP2C9CYP2D6 | |
| SCHEMBL3866762 | 0.89 | KMT2A (0.66) | SMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL29818241 | 0.85 | TSHR (0.73) | SMN1; SMN2ALDH1A1KDM4EGAATSHR | |
| SCHEMBL10192030 | 0.85 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1KDM4EGAATSHR | |
| SCHEMBL12459935 | 0.85 | CD274 (0.79) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP2C9 | |
| SCHEMBL1382764 | 0.84 | SMN1; SMN2 (0.95) | SMN1; SMN2ALDH1A1KDM4EGAATSHR | |
| SCHEMBL12334129 | 0.83 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1KDM4EGAATSHR | |
| SCHEMBL12305542 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KDM4EGAATSHR | |
| SCHEMBL14023396 | 0.82 | LMNA (0.61) | SMN1; SMN2ALDH1A1KDM4ETSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456166-B | 5-substituted amino-3-methylpyrido [2,3-d ] pyrimidine compound and preparation and application thereof | 沈阳药科大学 | 2023-06-16 | — | — | CN | disclosed |
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| CN-114456166-A | 5-substituted amino-3-methylpyrido [2,3-d ] pyrimidine compound and preparation and application thereof | 沈阳药科大学 | 2022-05-10 | — | — | CN | disclosed |
| EP-3984534-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | Peking University (CN) | 2022-04-20 | — | — | EP | disclosed |
| WO-2020253802-A1 | DIARYLAMIDE COMPOUND AND APPLICATION THEREOF | 北京大学 | 2020-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230045031-A1 | Diarylamide Compound and Application Thereof | SLC14A1, SLC28A1, SLC28A2 | SMN1; SMN2 4727/4885ALDH1A1 903/4885KDM4E 3421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.