Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | TRHR | P34981 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12250682 | 0.89 | HDAC3 (0.38) | HDAC3HDAC1HDAC10HDAC11HDAC8 | |
| SCHEMBL12228297 | 0.86 | TRHR (0.49) | TRHR | |
| SCHEMBL14468463 | 0.81 | L3MBTL1 (0.42) | HDAC3HDAC1HDAC10HDAC11HDAC8 | |
| SCHEMBL12250683 | 0.80 | HDAC3 (0.39) | HDAC3HDAC1HDAC10HDAC11HDAC8 | |
| SCHEMBL14543240 | 0.80 | TRHR (0.40) | HDAC3HDAC1HDAC10HDAC11HDAC8 | |
| SCHEMBL12228302 | 0.77 | TRHR (0.48) | TRHR | |
| SCHEMBL12250684 | 0.74 | TRHR (0.37) | HDAC3HDAC1HDAC10HDAC11HDAC8 | |
| SCHEMBL12228298 | 0.72 | TRHR (0.47) | TRHR | |
| SCHEMBL14468464 | 0.72 | TRHR (0.38) | TRHRL3MBTL1 | |
| SCHEMBL14468348 | 0.70 | L3MBTL1 (0.34) | TRHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202279-B1 | Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders | GEORGETOWN UNIVERSITY (US) | 2007-04-10 | — | — | US | disclosed |