Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228946 | 0.92 | MLYCD (0.44) | TP53MLYCDAGTR1AGTR2 | |
| SCHEMBL14229161 | 0.92 | TP53 (0.38) | TP53MLYCDMAPT | |
| SCHEMBL14228947 | 0.89 | MLYCD (0.38) | TP53MLYCDMAPT | |
| SCHEMBL14200618 | 0.85 | — | — | |
| SCHEMBL14228877 | 0.83 | MLYCD (0.43) | TP53MLYCDAGTR1AGTR2 | |
| SCHEMBL14229040 | 0.83 | MLYCD (0.43) | TP53MLYCDMAPTAGTR1AGTR2 | |
| SCHEMBL14200634 | 0.77 | MLYCD (0.35) | MLYCDAGTR1AGTR2 | |
| SCHEMBL14200619 | 0.77 | PDK1 (0.32) | — | |
| SCHEMBL14229163 | 0.76 | — | — | |
| SCHEMBL14229172 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |